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Nerve-related symptoms such as tingling or numbness may take several weeks or months to fully improve

DOI: 10.1056/NEJMoa2502081 Davies MJ, Bajaj HS, Broholm C, Christiansen E, Fink LN, Hussein Z, et al

Central administration of GLP-1RAs or SGLT-2is could increase the expression of c-Fos in neurons within the PVN, amygdala, NTS, AP, and ARC, 56,96 which was consistent with the expression of GLP-1R/SGLT-2 in the whole CNS

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